Medical adhesive (glue) closure

Medical adhesive (glue) closure seals a faulty vein with medical glue delivered through a catheter, instead of heat. It is done in our rooms under local anaesthetic, takes 20 to 30 minutes and needs no tumescent injections along the vein. It is generally not funded by South African medical schemes.

After treatment, call us if you notice

  • new swelling or pain in the calf of the treated leg
  • fever, or redness that is spreading
  • a skin reaction or itch along the treated vein after glue closure
  • changes in your vision after foam sclerotherapy

Call the centre that treated you. For breathlessness or chest pain, call 10177 or 112.

Key facts

Anaesthetic
Local
Procedure time
20–30 minutes
Where it's done
In our rooms, no hospital admission
Back to normal activity
Within a day

The circulatory system is made up of both veins and arteries. Arteries deliver fresh oxygen-rich blood from the heart to all tissues and veins then collect the oxygen-depleted blood again and transport it back to the heart. The heart will pump blood through the arteries, but not all the way through the veins.

In the lower limbs, blood requires a different transport system to return it, against gravity, back to the heart. This transport system is made up of a pump again, the “calf pump” and one way valves within the veins. It is for this reason that walking is a great way to keep your legs healthy, since the calf pump is activated all the time.

Broken one-way valves in the legs will cause blood to flow back through the vein and pool in the lower legs, this is known as venous reflux, and often presents as varicose veins. Varicose veins are large blue tortuous vessels that bulge from the surface of the skin.

Medical adhesive (glue) closure of a varicose vein

Can glue be used to treat varicose veins?

Medical adhesive (glue) closure is a minimally invasive in-office treatment for varicose veins and Chronic Venous Insufficiency (CVI) in which a vein specialist inserts an endovenous catheter (we use the VenaSeal™ system) to deliver glue, collapse and close enlarged leg veins. After the vein is sealed shut, blood then naturally re-routes to other healthy veins in the leg.

How does it work?

The procedure is performed in an office operating room under local anaesthetic, minimal preparation by the patient is required. It truly is a walk-in walk-out procedure that takes 20-30 minutes to perform. The procedure does not require hospital admission or a general anaesthetic.

To perform the procedure, Dr Blignaut maps out the leg veins to be treated prior to surgery using a duplex ultrasound. During the procedure, a small needle is inserted just below the knee. (This needle is the same size as a regular drip in the arm). This needle is replaced by a plastic cannula that allows for the passage of the catheter into the vein. No further injections are required. Once the catheter has been placed under ultrasound guidance, a precise amount of glue is delivered to the vein. Mild pressure allows the vein to be glued shut immediately, leaving a sealed vein. Upon completion, the catheter is removed from the leg. Most patients report little or manageable discomfort during the procedure. Mild tenderness or bruising may occur afterwards. For anxious or needle phobic patients we can give a mild sedative before or during the procedure. Patients leave the room once the procedure is complete. If no sedation was used, they may drive themselves home.

You will be encouraged to walk every day, but to refrain from strenuous activity for at least a week. Most patients who undergo glue treatment of their varicose veins typically resume normal activities within a day.

Is glue closure right for me?

Endovenous techniques have replaced traditional open surgery for many suitable patients12. The appropriate treatment depends on venous anatomy, reflux pattern, previous treatment and individual clinical circumstances. Open surgery remains appropriate in selected cases.

Cyanoacrylate closure differs from the thermal techniques: because it seals the vein with an adhesive rather than heat, no tumescent anaesthetic is required. That means a single needle puncture per vein rather than a series of injections along its length, and no risk of thermal injury to nearby nerves. Some patients find this preferable, and it can suit veins in positions where heat would be less appropriate.

Patients with symptomatic superficial vein reflux, as demonstrated on a duplex scan, are generally suitable candidates for this procedure. Deep venous reflux does not by itself rule out treatment: many patients with both deep and superficial reflux still benefit from treating the superficial veins. Suitability depends on the duplex findings, your symptoms and skin changes, and whether the deep veins are obstructed, for example after a previous DVT. The only way to establish whether glue closure suits you is a duplex scan performed by a vein specialist.

Your assessment is performed by Dr Johan Blignaut and includes duplex mapping before treatment is recommended. Treatment is selected according to your venous anatomy, not simply according to the veins visible on the skin.

Glue closure is a newer treatment option than radiofrequency or laser ablation. It is not funded by most South African medical schemes, which is a practical consideration in choosing between it and the thermal techniques — see the pricing section below.

Pricing and medical schemes

Cyanoacrylate glue closure is generally not funded by South African medical schemes, and in most cases the procedure is payable by the patient. Cover can differ between schemes and between options, so we confirm your individual benefits before your procedure rather than relying on general guidance.

For current fees and how medical schemes pay, see fees and medical aid.

Contact your nearest vein centre and we will check your specific benefits.

References

  1. De Maeseneer MG, Kakkos SK, Aherne T, et al. European Society for Vascular Surgery (ESVS) 2022 clinical practice guidelines on the management of chronic venous disease of the lower limbs. Eur J Vasc Endovasc Surg. 2022;63(2):184–267. ESVS guideline
  2. Gloviczki P, Lawrence PF, Wasan SM, et al. The 2022 SVS, AVF and AVLS clinical practice guidelines for the management of varicose veins of the lower extremities. Part I. J Vasc Surg Venous Lymphat Disord. 2023;11(2):231–61. Journal

Not sure which treatment is right for you? See our side-by-side comparison of radiofrequency ablation, EVLA, glue closure and foam sclerotherapy, and how the choice is made.

Videos

Short videos by Dr Johan Blignaut. They load from YouTube only when you press play.

  • Medical adhesive (glue) closure 2:11

What does it cost?

Costs depend on your assessment and your medical scheme. Fees, what they include and how schemes pay are on one page.

Fees and medical aid

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